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Category:  Osteoporosis
Contents: Alendronate sodium

 

Fosamax, Alendronate is in a class of medications used to strengthen bone. Fosamax is prescribed for the prevention and treatment of osteoporosis, the brittle bone disease, in postmenopausal women. Fosamax is also used to increase bone mass in men with osteoporosis, and is prescribed for both men and women who have developed a form of osteoporosis sometimes caused by steroid medications such as prednisone. Fosamax drug can also be used to relieve Paget's disease of bone, a painful condition that weakens and deforms the bones.


All about Fosamax

Drug Class: What is Fosamax and why is it prescribed?
Drug Mechanism: How does Fosamax work?
Dosage: How should you take Fosamax?
Possible food and drug interactions when taking Fosamax
Special information on Fosamax
Fosamax side effects



Drug Class: What is Fosamax and why is it prescribed?

Fosamax, Alendronate is in a class of medications used to strengthen bone. It is prescribed for the prevention and treatment of osteoporosis, the brittle bone disease, in postmenopausal women. It is also used to increase bone mass in men with osteoporosis, and is prescribed for both men and women who have developed a form of osteoporosis sometimes caused by steroid medications such as prednisone. This drug can also be used to relieve Paget's disease of bone, a painful condition that weakens and deforms the bones.


 

 

Drug Mechanism: How does Fosamax work?

Bone is in a constant state of remodeling, whereby old bone is removed by cells called osteoclasts, and new bone is laid down by cells called osteoblasts.

It works by preventing bone from being broken down by osteoclasts (cells that break down bone). This indirectly causes an increase in bone formation - increasing the density of bones to make them stronger.



 

 

Dosage: How should you take Fosamax?

Fosamax is effective only when each Fosamax tablet is taken with a full glass of plain water first thing in the morning, at least 30 minutes before the first food, beverage, or other medication. If you can wait longer before eating or drinking, Fosamax medication will be absorbed well. Do not lie down for at least 30 minutes after taking Fosamax and avoid chewing or sucking on the Fosamax tablet; it can cause mouth sores.

You should take calcium and vitamin D supplements if you don't get enough in your diet. Avoid smoking and alcohol. Weight-bearing exercise can also strengthen bones.

Postmenopausal Osteoporosis

The usual Fosamax dose is one 10-milligram Fosamax tablet once a day or one 70-milligram Fosamax tablet once a week. Treatment continues for years.

Prevention Of Postmenopausal Osteoporosis

The usual Fosamax dosage is one 5-milligram Fosamax tablet once a day or one 35-milligram Fosamax tablet once a week.

Osteoporosis In Men

The usual Fosamax dosage is one 10-milligram Fosamax tablet once a day or one 70-milligram Fosamax tablet once a week.

Steroid-Induced Osteoporosis

The usual dose of Fosamax is one 5-milligram Fosamax tablet once a day, except for postmenopausal women not taking estrogen, who should take one 10-milligram Fosamax tablet once daily.

Paget's Disease

The usual Fosamax dose is 40 milligrams once a day for 6 months.

Fosamax Overdose: Any medication taken in excess can have serious consequences. If you suspect an overdose of Fosamax, seek medical attention immediately.

Symptoms of Fosamax overdose may include: Heartburn, inflammation of the esophagus or stomach, ulcer, upset stomach.

If you miss a Fosamax dose: If you are taking Fosamax on a daily basis, do not take a missed Fosamax dose later in the day, instead, skip it and go back to your regular Fosamax medication schedule the next morning.

If you are taking Fosamax once a week, take 1 tablet the morning after you remember, then return to your original once-weekly Fosamax schedule on the chosen day. Do not take 2 Fosamax tablets on the same day.

Fosamax Storage Instructions: Keep the container tightly closed, avoid moisture and store at room temperature.

Fosamax Preparations: Tablets available in 5 mg (daily), 10 mg (daily), 35 mg (daily), 70 mg (weekly)

 

 

 

Possible food and drug interactions when taking Fosamax

Combining aspirin with a Fosamax dosage of more than 10 milligrams per day will increase the likelihood of stomach upset.

Calcium supplements such as Caltrate, antacids such as Riopan, and some other oral medications will interfere with the absorption of Fosamax, so wait at least 30 minutes after taking Fosamax before you take anything else.

 

 

 

Special information on Fosamax

Special Information if you are pregnant or breastfeeding

The effects of Fosamax during pregnancy and breastfeeding have not been adequately studied. If you are pregnant or plan to become pregnant, notify your doctor immediately. It is not known whether Fosamax appears in breast milk. The drug is not recommended for nursing mothers.


Most Important Fact about Fosamax medication

For Fosamax to be effective, you must take the Fosamax tablets without food or other medications, exactly as directed.



 

 

Fosamax side effects

Side effects of Fosamax cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue using Fosamax.

More common Fosamax side effects may include: Abdominal pain, bone and joint pain, constipation, diarrhea, indigestion, muscle pain, nausea

Less common Fosamax side effects may include: Abdominal distention, acid backup, difficulty in swallowing, esophageal ulcers, gas, headache, stomach ulcers, vomiting

Rare Fosamax side effects may include: Changes in taste, esophageal blockage or perforation, eye pain, hives, inflammation of the stomach, mouth sores, muscle cramps, rash, skin redness, swollen face and throat.


Why should Fosamax drug not be prescribed?

You should not take Fosamax; if the calcium level in your blood is low. Avoid Fosamax if it causes an allergic reaction.


Special warnings about Fosamax medication:

Fosamax is not recommended for women on hormone replacement therapy, or for women with kidney problems.

Be sure to tell your doctor if you have trouble swallowing or have any digestive disease. Fosamax may cause problems in your esophagus such as inflammation, ulcers, bleeding, and in rare cases, blockage or perforation.